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大明国体昌盛却礼教严苛,女子地位低下,不得从医,隐疾难治。谭家为医学世家,祖上几代均为御医,因被奸人所陷害而遭遇灭顶之灾,从此留下祖训,后世不得行医。但聪慧的谈允贤从小耳濡目染,偷偷随祖母学习中医知识,不仅悬壶济世、妙手仁心,得到了普通百姓的赞扬和支持,更渐起救天下女子之心。由此,允贤不仅在学医道路上面临重重的困难和阻碍,更要面对封建礼教和世俗观念的冲击。但允贤凭借着对于医学事业的痴迷和热爱,克服重重困难,不仅在医学上广收博采、兼收并蓄、自成一派,更突破严苛的礼教束缚,开创并建立了女医制度,从救人身体到救人灵魂,再由救人到救国,传播弘扬了祖国医学文化,最终成为了一代女国医,名扬天下。
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